The San Francisco 49ers suffered their worst loss of the 2025 NFL season in Week 8, falling 26-15 to the Houston Texans on the road. The offense struggled, mana

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. The Texans are -151 money line favorites (risk $151 to win $100),

The NFL season continues when the Houston Texans host the San Francisco 49ers Sunday. Start time, how to watch, streaming and NFL TV schedule.

The San Francisco 49ers will face the Houston Texans in Week 8 of the NFL season on Sunday at NRG Stadium.

The first 29 minutes of Sunday's game against the Houston Texans were a disaster for the San Francisco 49ers, but they ended the first half with a bang. After Houston took a 16-0 lead, the 49ers got a big kick return from running back Brian Robinson that put the 49ers at Houston's 35 with under a minute to go.

George Kittle still believes the San Francisco 49ers have the "right guys" with the NFL trade deadline looming after the loss to the Houston Texans.

The 49ers have played some bad football this season. But Sunday was something else entirely: The 49ers played so poorly against the Houston Texans that it makes you question if they can ever win again. Their performance in a 29-15 loss was, in a word, awful.

One reason the 49ers didn't get flagged is because pulling is a penalty that NFL officials almost never call. According to Football Zebras, the last time a player got penalized for pulling a teammate came all the way back during a playoff game in January 1991, so it's been almost 35 years.