Novak Djokovic is still in the hunt for his 25th career Major title when he takes on No. 22 seed Italian Flavio Cobolli for a spot in the semifinals.

Indeed, for the first time in the Open Era, three of the top-five seeds were eliminated in the 1st Round of a women's major. On Thursday, 23-year-old Amanda Anisimova will aim to become the first American woman to reach the Wimbledon final since Serena Williams in 2019.