Epigenetic research has long emphasized the role of DNA and histone modifications, yet emerging evidence highlights the capacity of RNA to encode hereditary information across generations 1. Beyond ...

For decades, cancer research has focused on the dysregulation of various cellular pathways, including transcription, chromatin structure, proliferative signaling, RNA processing, and genomic integrity ...

Despite the evidence linking condensates with aggregation, a comprehensive framework of mechanisms by which LLPS compartments influence amyloid aggregation has yet to be established and systematically ...

Researchers use high-resolution imaging to reveal the dynamic structure of biomolecular condensates, shedding light on their role in health and disease. (Nanowerk News) Biomolecular condensates are ...

Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms. These regulatory proteins bind DNA, turn genes on or off, and ...

Researchers are discovering the electrochemical properties of biomolecular condensates which could help in development of cancer or ALS treatments. Much of cell behavior is governed by the actions of ...

Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA ...

Researchers provide a new framework for designing soft materials that mimic a form of molecular organization seen in living systems. (Nanowerk News) Newly developed DNA nanostructures can form ...

Proteins, which fulfil most of the functions in our body by interacting with other proteins, face a dilemma – they move around the cell with 40 million potential interaction partners. Finding the ...

Novel synthetic biomolecular condensates have been developed that can degrade intracellular oncogenic protein KRAS. Recently, researchers at Northwestern Medicine (IL, USA) developed a synthetic ...

A team of NYU chemists and physicists are using cutting-edge tools—holographic microscopy and super-resolution imaging—to unlock how cells build and grow tiny, dynamic droplets known as biomolecular ...

Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches ...