Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, particularly in tissues such as the bone marrow, intestine and skin; neurons and heart ...

A new review in the Journal of Translational Medicine consolidates how the replication-initiation protein ORC1 safeguards ...

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library—your genome, which totals more than 3 ...

"If it ain't broke, don't fix it," goes the old adage, which Rice University professor James Chappell completely ignored in a recent Nature Communications publication. In the study, Chappell describes ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin.

A study headed by researchers at NYU Langone Health has found that herpes simplex virus 1 (HSV-1) partially liquifies the tightly packed, gel-like interior of human cell nuclei to help copy itself ...

Most people will become infected with Epstein-Barr virus, or EBV, at some point in their lives. In addition to being a common ...