A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results ...

A new research paper was published on the cover of Aging, titled "Human senescent fibroblasts trigger progressive lung fibrosis in mice." Cell senescence has recently emerged as a potentially relevant ...

Cancer-associated fibroblasts (CAFs) get a bad rap. The protective, gel-like complex surrounding tumors have been thought to be a no-go for drugs and are known to enforce treatment resistance. But ...

Scientists have uncovered a hidden partnership between pancreatic cancer and the nervous system. Support cells in the ...

Cell-based therapies can be developed in various ways, but companies look for methods that are faster and more efficient. At Houston, TX-based FibroBiologics scientists turn fibroblasts into ...

Cancer-associated fibroblasts (CAFs) are crucial in melanoma metastasis, influencing tumor microenvironments and patient outcomes, especially in immunotherapy contexts. Single-cell RNA sequencing ...

Scientists have mapped underappreciated scaffolding cells in skin, known as fibroblasts. They show for the first time how fibroblasts go 'rogue' in many different diseases affecting multiple organs – ...

The central nervous system (CNS) consists of several types of cells having varied specialized functions. While many of these cell types have been studied, fibroblast cells in the CNS remain ...

Researchers found that nerves and cancer-supporting cells team up early to drive pancreatic cancer—breaking that alliance ...