A multinational research team led by Dr. Adnan Sljoka (RIKEN), Prof. R. Scott Prosser (Univ. of Toronto) with collaborations with Dr. Duy Phuoc Tran and Prof. Akio Kitao (Tokyo Tech) and Prof. Roger K ...

A number of membrane proteins that are present on the cell membrane control external and internal material transportation, cell protection and signal transmission. The diversity of functions of ...

G-protein coupled receptors (GPCRs) are seven-pass transmembrane proteins involved in numerous signaling pathways. Upon extracellular ligand binding and activation, members of this superfamily mediate ...

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane.

Signal transduction is a key mechanism that brings about several physiological responses in a cell. Aberrant signaling can result due to gene mutations or regulatory protein overexpression. It is ...

Using advanced imaging methods, researchers have gained insight into how a common target of drugs sends cellular signals, a finding that may lead to better and more precise therapeutics. Roughly a ...

A publication from Acta Pharmaceutica Sinica B discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a debilitating ...

The GPCR-targeting therapies market is expected to grow significantly in the coming years. This is due to the increasing number of patients who are being diagnosed with cancer, the growing awareness ...

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane.