Meredith Grey, Caterina Scorsone
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"Grey's Anatomy" is premiering the newest episode of its 22nd season on Thursday, Oct. 16 at 10 p.m. There are several ways to watch with a free live stream.
Grey's Anatomy, ABC's longest-running medical procedural series, premiered its milestone 450th episode (Season 22 Episode 2) titled We Built This City on October 16.
In the upcoming episode, "the team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations."
PRIMETIMER on MSN
Grey’s Anatomy season 22 episode guide and complete release schedule: What days do the new episodes drop?
Grey’s Anatomy Season 22 returns with explosive drama at Grey Sloan Memorial. New episodes filled with emotional twist and medical miracle will air Thursdays at 10 pm ET on ABC
ABC is officially confirmed to dish up another new episode of their hit medical drama Grey’s Anatomy tonight, October 16, 2025, and it will feature some surgeries mixed with chaos and more. This episode is the second one for this current season 22.
Viewers without cable can watch the latest episodes of “Grey’s Anatomy” live and on demand for free by signing up for trial offers from Fubo (5-day free trial), DirecTV (5-day free trial) or Hulu + Live TV (3-day free trial).
PRIMETIMER on MSN
Grey’s Anatomy Season 22 Episode 2 recap: Maggie gives a shocking news and Amelia plans on taking a break
Grey’s Anatomy season 22 celebrates its 450th episode where Maggie drops a shocking news about her pregnancy and Amelia decides to take a long over-due break
Grey's Anatomy's milestone 450th episode featured Maggie' return, her pregnancy reveal and Amelia taking a sabbatical in the explosion's aftermath.