A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its ...

A human kidney is built once, before birth, and the rules guiding its construction have been largely inferred from animal models. Researchers at Penn Medicine have now read those rules directly in ...

“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...