RNA-based therapeutics use RNA as a blueprint that enables cells to produce specific proteins—including proteins that can ...
At a virtual conference in November 2020, the winner of a biennial protein-structure-prediction challenge was announced: AlphaFold. Created by Google DeepMind, this computational tool had blown its ...
Researchers mapped RNA fragments embedded in human DNA, revealing a new genomic layer called the "ribome" that may shape gene ...
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RNA can form large 3D structures, suggesting a new role for it in the origin of life on Earth
Scientists long thought that when RNA kick-started life on Earth 4 billion years ago, it could form only small, simple structures. But new research shows that naturally occurring RNA molecules can ...
Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers led ...
National Cancer Institute researchers have developed a method called HORNET for characterizing 3D topological structures of large and flexible RNA molecules. Scientists used atomic force microscopy ...
In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic Acid (RNA) High-Order Folding Prediction Plus (RhoFold+). This deep ...
It's one of the origins-of-life chicken-or-egg problems: How could RNA have helped give rise to the first cells before there were cells to contain it?
SANTA CRUZ, CA — Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or “ribozyme,” that carries out a fundamental reaction ...
A team of researchers at Kumamoto University has uncovered a mechanism in the formation of harmful protein aggregates that lead to neurodegenerative diseases such as Parkinson's disease. The team, led ...
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