The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity
USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...
The white blood cells in question are cytotoxic T lymphocytes (CTLs), also known as killer T cells. These "warrior" cells ...
The challenge of managing relapsed or refractory B-cell malignancies continues to thwart the efforts of oncologists and ...
CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in ...
5don MSN
'Primed and ready': How one fast-acting type of white blood cell fights off infection in infants
From the moment they're born, newborns—or, specifically, their immune systems—must learn to fight germs without harming their own tissues.
Researchers found that zeaxanthin, long associated with eye health, may also boost the body’s immune response against cancer.
New research by the IU School of Medicine is looking at new ways to fight aggressive cancers. Right now the focus is on ...
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Asher Biotherapeutics, a biotechnology company developing precisely-targeted immunotherapies for cancer and infectious diseases, today announced a ...
Joseph Mikhael, MD, and Krina K. Patel, MD, MSc, discuss considerations for CAR T-Cell therapy in multiple myeloma, including ...
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