Cladribine, a nucleotide (deoxyadenosine) analogue, inhibits deoxyribonucleic acid (DNA) synthesis in proliferating lymphocytes, causing DNA damage and depleting their number by apoptosis and ...

Multiple sclerosis (MS) treatment could be on the brink of a significant breakthrough thanks to innovative research by Immunic Therapeutics. Speaking to Fierce Pharma, CEO Daniel Vitt shares insights ...

Mavenclad (cladribine) is a medicine used to treat relapsing forms of multiple sclerosis (MS) including relapsing-remitting MS and active secondary progressive MS. Relapsing forms of MS have temporary ...

Kesimpta is a medication used to treat relapsing forms of multiple sclerosis (MS) and clinically isolated syndrome (CIS). Kesimpta comes as a solution inside single-dose prefilled injection pens or ...

"Medical Journeys" is a set of clinical resources reviewed by doctors, meant for physicians and other healthcare professionals as well as the patients they serve. Each episode of this journey through ...

The astroglia (a class of neural cells) of patients with MS overproduce a channel protein known as connexin 43. This overproduction facilitates the release of pro-inflammatory chemicals that trigger a ...

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS), including the brain, spinal cord, and optic nerves. The body mistakenly attacks and damages the protective ...

Pediatric-onset MS (POMS) is more inflammatory than adult-onset MS, with frequent relapses and cognitive issues, affecting 7.6% of MS cases. The 2017 McDonald criteria improved POMS diagnostic ...

Multiple Sclerosis Awareness Month is a time to recognize those affected by the disease and the treatments available to ...

Dr. Stephen Hauser was a young resident at Harvard when he met his first patient with multiple sclerosis, a woman with a thriving professional life who’d been completely wiped out by her condition, ...