The Bears host the Bills in NFL preseason action at 8 p.m. ET on FOX, with Chicago's starters expected to take the field.

The Chicago Bears dominated the Buffalo Bills in their 38-0 preseason win. We're handing out grades to every unit.

The Buffalo Bills took on the Chicago Bears and lost in a 38-0 fashion in the second weekend of the 2025 NFL preseason. Sometimes the stats can tell the story of who performed well and who did not, but Pro Football Focus is there to provide a little bit more context.

Love him or hate him, Chicago Bears quarterback Caleb Williams certainly can draw a crowd. That was evident on Sunday night when the Bears welcomed the Buffalo Bills to town for a prime-time preseason matchup.

Sean McDermott thought his team was trending upward coming off a solid joint practice with the Chicago Bears. It didn’t translate to the preseason game. The Buffalo Bills head coach called his team’s 38–0 blowout loss to Chicago “not even close,

Yes, it was preseason but the 38-0 drubbing by the Chicago Bears is hard to see as anything other than a cloud for fans of the Buffalo Bills. There were some silver-lining plays though. Don’t believe?