The construction of piperidine alkaloids through asymmetric total synthesis represents a pivotal endeavour in modern organic chemistry, driven by the prevalence of the piperidine motif in bioactive ...
The molecular motif 1-azaspiro[3.3]heptane may look peculiar, with its two 4-membered rings that share a single carbon. But the structure can behave like a mimic of piperidine, a popular heterocycle ...
A new, two-step strategy for making substituted piperidines offers chemists a more efficient way to make these biologically relevant molecules. The method, which leverages enzymatic oxidation and ...
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