San Francisco quarterback Mac Jones sustained a knee sprain in the 49ers’ second preseason game on Saturday and won’t be available when the NFL team closes its preseason schedule on Saturday.

If you offer Kyle Shanahan some smelling salts then he's probably going to take a smell, he revealed to the media on Tuesday.

Now he has a different breakdown: if starting from scratch, who would he hire as head coach? San Francisco 49ers head coach ...

Before Los Angeles Chargers backup quarterback Trey Lance became one of the standout players of the ongoing preseason, he ...

The 49ers wisely have some key veterans, most prominently Nick Bosa, Christian McCaffrey and Trent Williams, on schedules ...

There's no clarity yet on which quarterback will start for the San Francisco 49ers in their final preseason game.

The 49ers will likely have several players on injured lists after cut-down day, with receiver Brandon Aiyuk (knee) and safety Malik Mustapha (knee) expected to miss at least the first four games on ...

Here's who stood out on Day 16 of 49ers training camp. Keep in mind, Mac Jones sprained his knee in the 49ers' preseason win ...

The NFL has finally realized that it doesn't make sense to provide smelling salts to players who may be using them to mask ...

Former Detroit Lions quarterback Nate Sudfeld signed with the San Francisco 49ers and will view for the chance to back up Brock Purdy.

The 49ers face injury concerns as Mac Jones targets Week 1 return as Brock Purdy’s reliable backup quarterback option.