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Nicotinic acetylcholine receptors in decreased NMJ stimulation
Structure & Normal Function: - nAChRs are ligand-gated channels activated by acetylcholine - Mature receptor: 5 subunits (2α, 1β, 1δ, 1ε) arranged in rosette around central channel - α subunits contain binding sites for acetylcholine and neuromuscular blocking agents Changes in Decreased NMJ Stimulation: - Upregulation of immature (fetal ...
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